Structure of PDB 6exn Chain P

Receptor sequence
>6exnP (length=73) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
TSHRPQLEARSGAKAAAYTPTGIEHARLLPGHTTLKYRKFSWRKGTAFGR
HKGYINDMTKSEYHQEFLHKHVR
3D structure
PDB6exn Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.
ChainP
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna P H5 R6 P7 L9 H3 R4 P5 L7
BS02 rna P R29 P32 G33 H34 T35 R27 P30 G31 H32 T33
BS03 rna P T3 S4 H5 R6 Q8 R12 K16 Y20 R29 L30 T1 S2 H3 R4 Q6 R10 K14 Y18 R27 L28
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0045292 mRNA cis splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0071013 catalytic step 2 spliceosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6exn, PDBe:6exn, PDBj:6exn
PDBsum6exn
PubMed29146871
UniProtQ03772|CWC15_YEAST Pre-mRNA-splicing factor CWC15 (Gene Name=CWC15)

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