Structure of PDB 5xte Chain P

Receptor sequence
>5xteP (length=196) Species: 9606 (Homo sapiens) [Search protein sequence]
SHTDIKVPDFSEYRRLEVLDSTKSSRESSEARKGFSYLVTGVTTVGVAYA
AKNAVTQFVSSMSASADVLALAKIEIKLSDIPEGKNMAFKWRGKPLFVRH
RTQKEIEQEAAVELSQLRDPQHDLDRVKKPEWVILIGVCTHLGCVPIANA
GDFGGYYCPCHGSHYDASGRIRLGPAPLNLEVPTYEFTSDDMVIVG
3D structure
PDB5xte Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
ChainP
Resolution3.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H239
Catalytic site (residue number reindexed from 1) H161
Enzyme Commision number 7.1.1.8: quinol--cytochrome-c reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES P C217 H219 L220 C222 C236 H239 C139 H141 L142 C144 C158 H161
BS02 PLX P Y115 T118 V125 Y37 T40 V47
Gene Ontology
Molecular Function
GO:0008121 ubiquinol-cytochrome-c reductase activity
GO:0051537 2 iron, 2 sulfur cluster binding
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5xte, PDBe:5xte, PDBj:5xte
PDBsum5xte
PubMed28844695
UniProtP47985|UCRI_HUMAN Cytochrome b-c1 complex subunit Rieske, mitochondrial (Gene Name=UQCRFS1)

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