Structure of PDB 5w66 Chain P

Receptor sequence
>5w66P (length=387) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KLIGHEAKLLFLKSFQFILKRQIRWLITEMRFPKEFEHVAKIIWLKILKT
INDQPQEELKLQLHMTSTISILYLASTHLSLPVYTCDYIKWICTAKMPYF
QASEILPKSWRIQLPNYYVSILEGSISPFNGQLYNKIALTCGMIHFKEFF
NSEISCQGLLLKLVMQCALPPEFYFYTKQVIEFEETDIRNLTLWERTDER
HTGRVSNHAELRVLSYFMLTINWMLSFDRDRQYPLKWILSLTESLTQRTT
TSESIGRNIVKVVYPDKPTSSDYFQWSEEETLEFLKWMEKQFLPTQTSME
MTIDQKIARRKLYKIFPLDREDTHQLTFIEDLQERYAKQTPFFPPARKEA
IGRLLTHIASQLLVDFAISKEQLKDCISRIKNACLHR
3D structure
PDB5w66 Structural mechanism of ATP-independent transcription initiation by RNA polymerase I.
ChainP
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna P H294 R504 N507 H201 R379 N382
BS02 dna P L152 K153 L154 Q155 Y210 G224 N228 R293 H294 T295 L59 K60 L61 Q62 Y117 G131 N135 R200 H201 T202
Gene Ontology
Molecular Function
GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
GO:0046872 metal ion binding
Biological Process
GO:0001188 RNA polymerase I preinitiation complex assembly
GO:0006360 transcription by RNA polymerase I
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
Cellular Component
GO:0000120 RNA polymerase I transcription regulator complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0070860 RNA polymerase I core factor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5w66, PDBe:5w66, PDBj:5w66
PDBsum5w66
PubMed28623663
UniProtP40992|RRN7_YEAST RNA polymerase I-specific transcription initiation factor RRN7 (Gene Name=RRN7)

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