Structure of PDB 5nfy Chain P

Receptor sequence
>5nfyP (length=133) Species: 229992 (SARS coronavirus Frankfurt 1) [Search protein sequence]
HHAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTH
TGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQ
IPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCD
3D structure
PDB5nfy Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
ChainP
Resolution3.382 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.50: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.4.22.69: SARS coronavirus main proteinase.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN P C74 C77 H83 C90 C76 C79 H85 C92
BS02 ZN P C117 C120 C119 C122
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0019079 viral genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:5nfy, PDBe:5nfy, PDBj:5nfy
PDBsum5nfy
PubMed29279395
UniProtP0C6X7|R1AB_SARS Replicase polyprotein 1ab (Gene Name=rep)

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