Structure of PDB 5mam Chain P
Receptor sequence
>5mamP (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB
5mam
Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules.
Chain
P
Resolution
2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
P
F1 V2 H5
F1 V2 H5
BS02
peptide
P
H5 G8 S9 V12 Y16 G23 F24 F25 Y26 P28
H5 G8 S9 V12 Y16 G23 F24 F25 Y26 P28
BS03
peptide
P
C7 L11 L15 C19 R22 G23 F24 F25 Y26 T30
C7 L11 L15 C19 R22 G23 F24 F25 Y26 T30
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:5mam
,
PDBe:5mam
,
PDBj:5mam
PDBsum
5mam
PubMed
28348075
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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