Structure of PDB 5cdw Chain P

Receptor sequence
>5cdwP (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
PHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQ
HFKVLRDGAGKYFLGVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
3D structure
PDB5cdw Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.
ChainP
Resolution2.602 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide P R15 R34 S36 S38 S44 H55 F56 K57 G69 K72 R11 R30 S32 S34 S40 H51 F52 K53 G65 K68
External links
PDB RCSB:5cdw, PDBe:5cdw, PDBj:5cdw
PDBsum5cdw
PubMed26645482
UniProtP62993|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)

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