Structure of PDB 4x23 Chain P

Receptor sequence
>4x23P (length=79) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
DNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYT
EHAKRKTVTAMDVVYALKRQGRTLYGFGG
3D structure
PDB4x23 A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C.
ChainP
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna P R35 R45 I46 S47 R78 K79 T80 R12 R22 I23 S24 R55 K56 T57 PDBbind-CN: Kd=0.1uM
BS02 dna P T30 P32 R36 R45 T7 P9 R13 R22 PDBbind-CN: Kd=0.1uM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:4x23, PDBe:4x23, PDBj:4x23
PDBsum4x23
PubMed23723239
UniProtP84040|H4_DROME Histone H4 (Gene Name=His4)

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