Structure of PDB 4g7o Chain P

Receptor sequence
>4g7oP (length=347) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
TSDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDPDL
IREVVRAKILGSARVRHIPGLKETLDPKTVEEIDQKLKSLPKEHKRYLHI
AREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEK
FEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTAR
QLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKD
SFYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLI
DGREHTLEEVGAFFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD
3D structure
PDB4g7o Structural basis of transcription initiation.
ChainP
Resolution2.993 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna P D326 S327 D250 S251
BS02 dna P D79 V81 R82 L85 H86 G89 L93 N191 R193 L194 F209 K226 F227 E228 F233 K234 S236 T237 Y238 T240 W241 D3 V5 R6 L9 H10 G13 L17 N115 R117 L118 F133 K150 F151 E152 F157 K158 S160 T161 Y162 T164 W165
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4g7o, PDBe:4g7o, PDBj:4g7o
PDBsum4g7o
PubMed23086998
UniProtQ5SKW1

[Back to BioLiP]