Structure of PDB 1nk2 Chain P

Receptor sequence
>1nk2P (length=77) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
ASDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTP
TQVKIWFQNHRYKTKRAQNEKGYEGHP
3D structure
PDB1nk2 Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity.
ChainP
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna P K109 K111 R113 V114 Q152 I155 N159 K163 K9 K11 R13 V14 Q52 I55 N59 K63 PDBbind-CN: Kd=0.19nM
BS02 dna P R110 K111 R112 R113 Y162 R10 K11 R12 R13 Y62 PDBbind-CN: Kd=0.19nM
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1nk2, PDBe:1nk2, PDBj:1nk2
PDBsum1nk2
PubMed9154919
UniProtP22808|VND_DROME Homeobox protein vnd (Gene Name=vnd)

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