Structure of PDB 6sv4 Chain Oc

Receptor sequence
>6sv4Oc (length=313) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
LVLRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDDQKFGV
PVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGETYQRFVGH
KSDVMSVDIDKKASMIISGSRDKTIKVWTIKGQCLATLLGHNDWVSQVRV
VPNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASP
DGTLIASAGKDGEIMLWNLAAKKAMYTLSAQDEVFSLAFSPNRYWLAAAT
ATGIKVFSLDPQYLVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLFAGYT
DNVIRVWQVMTAN
3D structure
PDB6sv4 RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
ChainOc
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Oc G63 S282 G57 S276
Gene Ontology
Molecular Function
GO:0001965 G-protein alpha-subunit binding
GO:0005080 protein kinase C binding
GO:0005092 GDP-dissociation inhibitor activity
GO:0043022 ribosome binding
GO:0045182 translation regulator activity
Biological Process
GO:0002181 cytoplasmic translation
GO:0006521 regulation of cellular amino acid metabolic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0010629 negative regulation of gene expression
GO:0017148 negative regulation of translation
GO:0061157 mRNA destabilization
GO:0070651 nonfunctional rRNA decay
GO:0072344 rescue of stalled ribosome
GO:1902660 negative regulation of glucose mediated signaling pathway
GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process
GO:1990145 maintenance of translational fidelity
GO:2001125 negative regulation of translational frameshifting
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6sv4, PDBe:6sv4, PDBj:6sv4
PDBsum6sv4
PubMed32203490
UniProtP38011|GBLP_YEAST Small ribosomal subunit protein RACK1 (Gene Name=ASC1)

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