Structure of PDB 7mdz Chain OO

Receptor sequence

>7mdzOO (length=136) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

SLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKAD
RDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSA
LRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL

3D structure

PDB

7mdz Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation.

Chain

Resolution

3.2 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	OO	H32 N38 D39 F41 H43 G49 K50 E51 T52 R55 T57 G59 M60 D65 R66 E68 R98 I135 P136 S137 D138 S139 T140 R141 K143 G144 G145 R146 R147 R149 R150	H17 N23 D24 F26 H28 G34 K35 E36 T37 R40 T42 G44 M45 D50 R51 E53 R83 I120 P121 S122 D123 S124 T125 R126 K128 G129 G130 R131 R132 R134 R135

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:7mdz, PDBe:7mdz, PDBj:7mdz
PDBsum	7mdz
PubMed	34403584
UniProt	G1T1F0\|RS14_RABIT Small ribosomal subunit protein uS11 (Gene Name=RPS14)