Structure of PDB 8g2z Chain OC

Receptor sequence
>8g2zOC (length=433) Species: 452467 (Tetrahymena thermophila CU428) [Search protein sequence]
MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSGDDAFNTFFSET
GAGKHVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARG
HYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLER
LSVDYGKKSKLGFTIYPSPQVSTAVVEPYNSILSTHSLLEHTDVAVMLDN
EAIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQ
TNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPANMMAKCD
PRHGKYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGIN
YQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVH
WYVGEGMEEGEFSEAREDLAALEKDYEEVGIET
3D structure
PDB8g2z Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins.
ChainOC
Resolution4.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP OC Q11 G12 Q15 E71 N101 S140 G143 T145 I171 N206 Y224 N228 Q11 G12 Q15 E65 N95 S134 G137 T139 I165 N200 Y218 N222
BS02 MG OC Q11 D69 E71 Q11 D63 E65
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g2z, PDBe:8g2z, PDBj:8g2z
PDBsum8g2z
PubMed37061538
UniProtP41351|TBA_TETTH Tubulin alpha chain

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