Structure of PDB 8vg2 Chain O

Receptor sequence
>8vg2O (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
HAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNS
IRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFK
CE
3D structure
PDB8vg2 Cryo-EM structure of FoxA1 and GATA4 in complex with H14 chromatosome
ChainO
Resolution3.04 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna O S174 Y175 R213 N216 S217 H220 R261 R262 K264 R265 S7 Y8 R46 N49 S50 H53 R94 R95 K97 R98
BS02 dna O L193 Y197 R219 H220 S223 W244 L260 R261 L26 Y30 R52 H53 S56 W77 L93 R94
External links
PDB RCSB:8vg2, PDBe:8vg2, PDBj:8vg2
PDBsum8vg2
PubMed
UniProtP55317|FOXA1_HUMAN Hepatocyte nuclear factor 3-alpha (Gene Name=FOXA1)

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