Structure of PDB 8u5h Chain O

Receptor sequence
>8u5hO (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQR
SAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB8u5h Cryo-EM structure of human DNMT3A N-terminal domain bound to H2AK119Ub nucleosome
ChainO
Resolution3.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide O L109 I112 L73 I76
BS02 dna O R42 R72 F84 R116 V117 T118 R6 R36 F48 R80 V81 T82
BS03 dna O R40 Y41 V46 R63 K64 L65 P66 R4 Y5 V10 R27 K28 L29 P30
Gene Ontology
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8u5h, PDBe:8u5h, PDBj:8u5h
PDBsum8u5h
PubMed
UniProtP02302|H3C_XENLA Histone H3.3C (Gene Name=h3-5)

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