Structure of PDB 8ro2 Chain O

Receptor sequence
>8ro2O (length=288) Species: 9606 (Homo sapiens) [Search protein sequence]
WEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPGVRMR
FKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGLSFKDDMPKSDVNK
EYYTQNMEREISNSDGTRPVGMLGKATSTSDMLLKLARTTPYYKRNRPHI
CSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGINDPVADKLL
KRASTMPRLDPPEDKTITTLYVGGLGDTITETDLRNHFYQFGEIRTITVV
QRQQCAFIQFATRQAAEVAAEKSFNKLIVNGRRLNVKW
3D structure
PDB8ro2 Mechanism for the initiation of spliceosome disassembly.
ChainO
Resolution3.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna O R35 E39 R56 C165 S166 F167 K174 R175 Y181 R21 E25 R42 C151 S152 F153 K160 R161 Y167
BS02 rna O R64 K66 E69 R159 Q196 I198 R201 K212 R216 R50 K52 E55 R145 Q182 I184 R187 K198 R202
External links
PDB RCSB:8ro2, PDBe:8ro2, PDBj:8ro2
PDBsum8ro2
PubMed38925148
UniProtQ9NW64|RBM22_HUMAN Pre-mRNA-splicing factor RBM22 (Gene Name=RBM22)

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