Structure of PDB 8ro1 Chain O

Receptor sequence

>8ro1O (length=342) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]

WEDSDFPILCETCLGNNPYMRMMKDKYGRECKICERPFTTFRWQPGKGAR
YKNTELCQTCAKVKNVCQTCMFDLEYGLPVQVRDHELQIADNIPKQGANR
DFFLQNVERTLGQGDGTQPIAQIANNMDQAAHDRLRRMGRTQPYYKRNAP
HICSFFVKGECKRGEECPYRHEKPTDPDDPLSRQNIRDRYYGTNDPVAEK
ILNRAAAAPTLSPPADTTITTLYIGNLGPSGAQQVTEKDLNDFFYQYGDI
RCLRVLTEKGCAFIEFTTREAAERAAERSFNKTFIKGKRLTIRWGTPVPS
VPILPVPDGLAAAPRSLVVPNVRPVKSSSIYYPSQDPTRLGA

3D structure

PDB

8ro1 Mechanism for the initiation of spliceosome disassembly.

Chain

Resolution

3.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	O	R36 R57 R65 C168 S169 F170 K173 C176 K177 R178 P183 Y184	R21 R42 R50 C153 S154 F155 K158 C161 K162 R163 P168 Y169
BS02	rna	O	R65 K67 E70 T84 C85 R162 H166 T190 L196 Q199	R50 K52 E55 T69 C70 R147 H151 T175 L181 Q184
BS03	ZN	O	C82 C85	C67 C70
BS04	ZN	O	C46 C49 C75	C31 C34 C60
BS05	ZN	O	C176 C182 H186	C161 C167 H171

External links

PDB	RCSB:8ro1, PDBe:8ro1, PDBj:8ro1
PDBsum	8ro1
PubMed	38925148
UniProt	Q22412

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