Structure of PDB 8qbt Chain O

Receptor sequence

>8qbtO (length=114) Species: 679895 (Escherichia coli BW25113) [Search protein sequence]

KSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAAST
VEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGRV
QALADAAREAGLQF

3D structure

PDB

8qbt Novel arrest peptides induce ribosome stalling by short circuiting the ribosomal peptidyltransferase activity

Chain

Resolution

2.2 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	O	R9 R10 T12 R13 R16 L18 L21 S91 F92 R94 Q98 Y99 R111 F117	R6 R7 T9 R10 R13 L15 L18 S88 F89 R91 Q95 Y96 R108 F114
BS02	rna	O	R15 R25 H29 R30 T31 P32 R33 H34 Y36 Q38 I40 G44 S45 E46 V47 V54 K63 Y64 N67 K68 Q98 H100 G101 R102	R12 R22 H26 R27 T28 P29 R30 H31 Y33 Q35 I37 G41 S42 E43 V44 V51 K60 Y61 N64 K65 Q95 H97 G98 R99

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8qbt, PDBe:8qbt, PDBj:8qbt
PDBsum	8qbt
PubMed	38503735
UniProt	P0C018\|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)