Structure of PDB 8oop Chain O

Receptor sequence
>8oopO (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
RAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTA
EILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPN
IQAVLLPKK
3D structure
PDB8oop Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
ChainO
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna O R11 A12 A14 R17 R32 R77 R1 A2 A4 R7 R22 R67
BS02 dna O R11 K13 R29 R42 V43 G44 A45 K75 T76 R77 K118 R1 K3 R19 R32 V33 G34 A35 K65 T66 R67 K108
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008285 negative regulation of cell population proliferation
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8oop, PDBe:8oop, PDBj:8oop
PDBsum8oop
PubMed37384673
UniProtQ93077|H2A1C_HUMAN Histone H2A type 1-C (Gene Name=H2AC6)

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