Structure of PDB 8ic2 Chain O

Receptor sequence

>8ic2O (length=318) Species: 10090 (Mus musculus) [Search protein sequence]

YGLLAAILGDKTTKKLHEYSRVITVDGNICSGKNKLAKEIAQQLGMKHYP
EAGIQYSSTTTGDGRPLDIEFSGSCSLEKFYDDPKSNDGNSYRLQSWLYA
SRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGYIRKQCVDHY
NEIKRLTLPEYLPPHAVIYIDVPVPEVQSRIQKKGDPHEMKVTSAYLQDI
ENAYKKTFLPKMSEMCEVLVYDSWEAEDPTKVVEDIEYLKYNKGPWLKQD
DWTFHYLRMLVQDKTEVLNYTTIPVYLPEITIGAHQGSRIYNSFRELPGR
KYAPGYNAEVGDKWIWLK

3D structure

PDB

8ic2 Respiratory complex CI:CIII2, type I, PERK -/- mouse under cold temperature

Chain

Resolution

6.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ADP	O	I66 C67 K70 N71 E88 F117 Y118 Q132 L135 R161 F169 E226	I29 C30 K33 N34 E51 F80 Y81 Q95 L98 R124 F132 E189

External links

PDB	RCSB:8ic2, PDBe:8ic2, PDBj:8ic2
PDBsum	8ic2
PubMed
UniProt	Q99LC3\|NDUAA_MOUSE NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Gene Name=Ndufa10)

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