Structure of PDB 8he5 Chain O

Receptor sequence
>8he5O (length=516) Species: 460519 (Komagataella phaffii) [Search protein sequence]
NIDDGDDAFYNARLNAWVTKRSQDEEEWFKPHPTKQDAILDDDYRLPGDV
YPALFDYQKTCVQWLWELYLQKVGGILGDEMGLGKTVQIISFIAGLHYTK
KLNKPVIVVCPATVLRQWCNEFHRWWPPLRVVILHAIGESRVKELIDSVF
TRGHVIITTYVGLRIYSKHLLKRDWGYAILDEGHKIRNPNSDISLTCKQL
RTPNRVILSGTPIQNNLTELWSLFDFIFPGRLGTLPVFQNQFAIPINVGN
LQVQVGYKCAVTLKDLISPYLLRRVPKKSEMVLFCKLTAPQHALYEKFLR
SDELSRILQGKRQVLYGIDILRKICNHPDLVDVHAKRRSKKDPTYGSASK
SGKMQVVKKLLELWKSQGHKTLLFTQTRQMLDILESFLERLNAKGAEEED
FVPFKFLRMDGTTSIGVRQSLVDVFNNDPSYNVFLLTTRVGGLGVNLTGA
NRVIIYDPDWNPSTDVQARERAWRLGQKKDVTIYRLMIAGSIEEKIYHRQ
IFKQFLTNKILKDPKQ
3D structure
PDB8he5 Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
ChainO
Resolution6.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna O D478 V614 L615 S714 R799 D192 V314 L315 S414 R499
BS02 dna O A362 V447 R606 K611 R612 L615 Y616 D619 K623 Q676 T677 R678 Q679 D710 G711 R739 V740 A112 V161 R306 K311 R312 L315 Y316 D319 K323 Q376 T377 R378 Q379 D410 G411 R439 V440
Gene Ontology
Molecular Function
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016787 hydrolase activity
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006338 chromatin remodeling
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8he5, PDBe:8he5, PDBj:8he5
PDBsum8he5
PubMed37120012
UniProtC4R198

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