Structure of PDB 8fug Chain O

Receptor sequence
>8fugO (length=73) Species: 9606 (Homo sapiens) [Search protein sequence]
VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIG
SLDNITHVPGGGNKKIETHKLTF
3D structure
PDB8fug Stacked binding of a PET ligand to Alzheimer's tau paired helical filaments.
ChainO
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y9H O Q351 S352 K353 Q46 S47 K48
Gene Ontology
Molecular Function
GO:0008017 microtubule binding
GO:0015631 tubulin binding

View graph for
Molecular Function
External links
PDB RCSB:8fug, PDBe:8fug, PDBj:8fug
PDBsum8fug
PubMed37236970
UniProtP10636|TAU_HUMAN Microtubule-associated protein tau (Gene Name=MAPT)

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