Structure of PDB 8e30 Chain O

Receptor sequence

>8e30O (length=142) Species: 562 (Escherichia coli) [Search protein sequence]

MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDT
GDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERV
IEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI

3D structure

PDB

8e30 Potential for clicked streptogramin analogs

Chain

Resolution

1.91 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	O	K2 T3 E9 W15 T24 G26 R27 T30 R37 K39 H47 Y53 T65 K68 K72 Y75 H76 H77 T78 H80 I81 I84 R96 E102 A104 G107 M108 P110 P113 L114 R116 R120 H132 A134 Q135	K2 T3 E9 W15 T24 G26 R27 T30 R37 K39 H47 Y53 T65 K68 K72 Y75 H76 H77 T78 H80 I81 I84 R96 E102 A104 G107 M108 P110 P113 L114 R116 R120 H132 A134 Q135

Gene Ontology

	Molecular Function
GO:0003729	mRNA binding
GO:0003735	structural constituent of ribosome
GO:0008270	zinc ion binding
GO:0048027	mRNA 5'-UTR binding
GO:0070180	large ribosomal subunit rRNA binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0017148	negative regulation of translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:8e30, PDBe:8e30, PDBj:8e30
PDBsum	8e30
PubMed
UniProt	P0AA10\|RL13_ECOLI Large ribosomal subunit protein uL13 (Gene Name=rplM)