Structure of PDB 8bws Chain O

Receptor sequence
>8bwsO (length=568) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
LVTPEDVMTISSLEQRTLNPDLFLYKELVKAHLGERAASVIGMLVALGRL
SVRELVEKIDGMDVDSVKTTLVSLTQLRCVKYLQETAISGKKTTYYYYNE
EGIHILLYSGLIIDEIITQMRVNDEEEHKQLVAEIVQNVISLGSLTVEDY
LSSVTSDSMKYTISSLFVQLCEMGYLIQISKLHYTPIEDLWQFLYEKHYK
NIPRNSPLSDLKKRSQAKMNAKTDFAKIINKPNELSQILTVDPKTSLRIV
KPTVSLTINLDRFMKGRRSKQLINLAKTRVGSVTAQVYKIALRLTEQKSP
KIRDPLTQTGLLQDLEEAKSFQDEAELVEEKTPGLTFNAIDLARHLPAEL
DLRGSLLSRKPHSASLINSHLKILASSNFPFLNETKPGVYYVPYSKLMPV
LKSSVYEYVIASTLGPSAMRLSRCIRDNKLVSEKIINSTALMKEKDIRST
LASLIRYNSVEIQEVPRTADRSASRAVFLFRCKETHSYNFMRQNLEWNMA
NLLFKKEKLKQENSTLLKKANRDDVKGRENELLLPSELNQLKMVNERELN
VFARLSRLLSLWEVFQMA
3D structure
PDB8bws Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
ChainO
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna O S233 D234 L235 S209 D210 L211
Gene Ontology
Molecular Function
GO:0001056 RNA polymerase III activity
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006383 transcription by RNA polymerase III
GO:0006384 transcription initiation at RNA polymerase III promoter
GO:0006386 termination of RNA polymerase III transcription
GO:0042797 tRNA transcription by RNA polymerase III
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bws, PDBe:8bws, PDBj:8bws
PDBsum8bws
PubMed36977686
UniProtP32349|RPC3_YEAST DNA-directed RNA polymerase III subunit RPC3 (Gene Name=RPC82)

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