Structure of PDB 8bwf Chain O

Receptor sequence
>8bwfO (length=78) Species: 9606 (Homo sapiens) [Search protein sequence]
PSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEA
ANTMVNYYTSVTPVLRGQPIYIQFSNHK
3D structure
PDB8bwf Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding.
ChainO
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide O E72 I76 L80 T86 N87 M90 E16 I20 L24 T30 N31 M34
BS02 peptide O T71 G73 E74 S77 T15 G17 E18 S21
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:8bwf, PDBe:8bwf, PDBj:8bwf
PDBsum8bwf
PubMed37564416
UniProtP26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (Gene Name=PTBP1)

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