Structure of PDB 8b7z Chain O

Receptor sequence
>8b7zO (length=258) Species: 39490 (Eubacterium ramulus) [Search protein sequence]
ADFKFEPMRSLIYVDCVSEDYRPKLQRWIYKVAIPDSISQFEPYVTKYAF
YPSFPIPPQGDRFGYARMQLTEHHWLVSDLDPRLEIKAIAETFPMDVLVW
QGQIPAEGNPFIFAFLPMWWEKDLKGKGRTIEDGANYRFNMTIGFPEGVD
KAEGEKWLFEKVVPILQAAPECTRVLASAVKKDINGCVMDWVLEIWFENQ
SGWYKVMVDDMKALEKPSWAQQDAFPFLKPYHNVCSAAVADYTPSNNLAN
YRGYITMR
3D structure
PDB8b7z Structural Basis for (2 R ,3 R )-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus .
ChainO
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.5.1.6: chalcone isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DQH O S37 F41 Y48 F50 T71 H73 W75 D79 Q101 F135 F137 S37 F41 Y48 F50 T71 H73 W75 D79 Q101 F111 F113
BS02 DQH O W28 A33 Q40 K87 E91 F93 F135 W28 A33 Q40 K87 E91 F93 F111
BS03 DQH O P194 E195 K229 P170 E171 K205
BS04 DQH O E195 E222 E171 E198
BS05 DQH O R153 G158 A159 E222 R129 G134 A135 E198
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0045430 chalcone isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:8b7z, PDBe:8b7z, PDBj:8b7z
PDBsum8b7z
PubMed36432010
UniProtV9P0A9

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