Structure of PDB 8a57 Chain O

Receptor sequence

>8a57O (length=144) Species: 169963 (Listeria monocytogenes EGD-e)

LHELKPSEGSRKERNRVGRGTGSGNGKTSGRGHKGQKARSGGGVRLGFEG
GQLPLFRRIPKRGFTNINRKEFAIVNLDVLNRFEDGTEVTPELLVETGII
RNEKSGIKILSNGNIEKKLTVKANKFSAAAKEAIEAAGGKTEVI

3D structure

• PDB: 8a57 Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes.
• Chain: O
• Resolution: 2.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	O	H4 E5 L6 K7 S9 G11 S12 R13 K14 R16 N17 R18 V19 G20 R21 G22 G24 S25 G28 K29 T30 S31 G32 R33 G34 H35 K36 G37 Q38 K39 R41 S42 G43 V46 R47 L48 F50 E51 G52 G53 Q54 L55 F58 R59 R60 P62 K63 R64 G65 F66 N68 I69 N70 R71 I76 N78 R84 R103 K110 L112 S113 N114 S129 A130	H2 E3 L4 K5 S7 G9 S10 R11 K12 R14 N15 R16 V17 G18 R19 G20 G22 S23 G26 K27 T28 S29 G30 R31 G32 H33 K34 G35 Q36 K37 R39 S40 G41 V44 R45 L46 F48 E49 G50 G51 Q52 L53 F56 R57 R58 P60 K61 R62 G63 F64 N66 I67 N68 R69 I74 N76 R82 R101 K108 L110 S111 N112 S127 A128

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8a57, PDBe:8a57, PDBj:8a57
• PDBsum: 8a57
• PubMed: 36300626
• UniProt: Q8Y447|RL15_LISMO Large ribosomal subunit protein uL15 (Gene Name=rplO)