Structure of PDB 7z53 Chain O

Receptor sequence
>7z53O (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
CPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPG
VKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFT
PEPAA
3D structure
PDB7z53 The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation.
ChainO
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.2.2: myeloperoxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEC O M253 G256 Q257 D260 D264 F265 T266 M87 G90 Q91 D94 D98 F99 T100
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0020037 heme binding
Biological Process
GO:0006979 response to oxidative stress

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Molecular Function
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Biological Process
External links
PDB RCSB:7z53, PDBe:7z53, PDBj:7z53
PDBsum7z53
PubMed36150500
UniProtP05164|PERM_HUMAN Myeloperoxidase (Gene Name=MPO)

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