Structure of PDB 7tz6 Chain O

Receptor sequence
>7tz6O (length=423) Species: 9913 (Bos taurus) [Search protein sequence]
VPPHPQDLEFTRLPNGLVIASLENYAPASRIGLFIKAGSRYENSNNLGTS
HLLRLASSLTTKGASSFKITRGIEAVGGKLSVTSTRENMAYTVECLRDDV
DILMEFLLNVTTAPEFRRWEVAALQPQLRIDKAVALQNPQAHVIENLHAA
AYRNALANSLYCPDYRIGKVTPVELHDYVQNHFTSARMALIGLGVSHPVL
KQVAEQFLNIRGGLGLSGAKAKYHGGEIREQNGDSLVHAALVAESAAIGS
AEANAFSVLQHVLGAGPHVKRGSNATSSLYQAVAKGVHQPFDVSAFNASY
SDSGLFGFYTISQAASAGDVIKAAYNQVKTIAQGNLSNPDVQAAKNKLKA
GYLMSVESSEGFLDEVGSQALAAGSYTPPSTVLQQIDAVADADVINAAKK
FVSGRKSMAASGNLGHTPFIDEL
3D structure
PDB7tz6 Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes.
ChainO
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide O R70 L71 E90 K95 L96 S97 V98 T99 S100 Q156 I160 D308 S310 F312 N313 A314 Y325 R54 L55 E74 K79 L80 S81 V82 T83 S84 Q140 I144 D292 S294 F296 N297 A298 Y309
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tz6, PDBe:7tz6, PDBj:7tz6
PDBsum7tz6
PubMed37236355
UniProtP23004|QCR2_BOVIN Cytochrome b-c1 complex subunit 2, mitochondrial (Gene Name=UQCRC2)

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