Structure of PDB 7sym Chain O

Receptor sequence

>7symO (length=149) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIG
VILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKH
LERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALV

3D structure

PDB

7sym Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway

Chain

Resolution

4.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	O	G2 R3 M4 P7 K9 L11 S12 S14 A15 P47 S48 G51 R55 A61 Q62 R64 K70 L72 R73 H90 K94 H101 N105 K107 D108 K109 F113 R114 L117 S120 R121 R124 R127 Y128 K132	G1 R2 M3 P6 K8 L10 S11 S13 A14 P46 S47 G50 R54 A60 Q61 R63 K69 L71 R72 H89 K93 H100 N104 K106 D107 K108 F112 R113 L116 S119 R120 R123 R126 Y127 K131

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0070181	small ribosomal subunit rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Cellular Component

External links

PDB	RCSB:7sym, PDBe:7sym, PDBj:7sym
PDBsum	7sym
PubMed
UniProt	G1SP51\|RS13_RABIT Small ribosomal subunit protein uS15 (Gene Name=RPS13)

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