Structure of PDB 7qsm Chain O

Receptor sequence
>7qsmO (length=320) Species: 9913 (Bos taurus) [Search protein sequence]
LQYGPLAYILGEKATKKMTEKSKLITVDGNICSGKSKLAKEIAEKLGLKH
FPEAGIHYVDSTTGDGKPLPVQFSGNCSLEKFYDDPKSNDGNSYRLQAWL
YASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVD
HYNQVKKVTICEYLPPHVVVYVDVPVPEVQSRIQKKGNPHEMKITSAYLQ
DIENAYKGTFLPEMSEKCEVLQYSAWEAQDAEKVVEDIEYLKYDKGPWLD
QNDRKLHKLRMLVQDKLEVLNYTSIPVFLPEVTVGAHQSDQVFQEFTELP
GRKYRAGYNEDVGDKWIWLK
3D structure
PDB7qsm Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
ChainO
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GTP O I31 C32 S33 G34 K35 S36 E53 L79 F82 Y83 Q97 L100 R104 R126 F134 E191 I31 C32 S33 G34 K35 S36 E53 L79 F82 Y83 Q97 L100 R104 R126 F134 E191
Gene Ontology
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0045271 respiratory chain complex I

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7qsm, PDBe:7qsm, PDBj:7qsm
PDBsum7qsm
PubMed35589726
UniProtP34942|NDUAA_BOVIN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Gene Name=NDUFA10)

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