Structure of PDB 7m5c Chain O

Receptor sequence
>7m5cO (length=151) Species: 9606 (Homo sapiens) [Search protein sequence]
EEQVAQDTEEVFRSYVFYRHQQEQEADPEMVTLPSSTMGQVGRQLAIIGD
DINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLG
FGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNL
C
3D structure
PDB7m5c Structural basis of BAK activation in mitochondrial apoptosis initiation.
ChainO
Resolution3.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide O D84 I85 R88 Y89 E92 F93 M96 H99 I114 S117 L118 N124 G126 R127 L183 D51 I52 R55 Y56 E59 F60 M63 H66 I81 S84 L85 N91 G93 R94 L150
BS02 CU O H141 H145 H108 H112
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:7m5c, PDBe:7m5c, PDBj:7m5c
PDBsum7m5c
PubMed35017502
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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