Structure of PDB 6zvh Chain O

Receptor sequence
>6zvhO (length=140) Species: 9606 (Homo sapiens) [Search protein sequence]
EQVISLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMK
VKADRDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPG
AQSALRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL
3D structure
PDB6zvh EDF1 coordinates cellular responses to ribosome collisions.
ChainO
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna O N38 D39 F41 H43 G49 K50 E51 T52 R55 T57 G59 M60 D65 R66 R104 I135 P136 S137 D138 S139 T140 R141 K143 R146 R147 R149 R150 N27 D28 F30 H32 G38 K39 E40 T41 R44 T46 G48 M49 D54 R55 R93 I124 P125 S126 D127 S128 T129 R130 K132 R135 R136 R138 R139
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0045182 translation regulator activity
GO:0048027 mRNA 5'-UTR binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006417 regulation of translation
GO:0030218 erythrocyte differentiation
GO:0030490 maturation of SSU-rRNA
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0014069 postsynaptic density
GO:0015935 small ribosomal subunit
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zvh, PDBe:6zvh, PDBj:6zvh
PDBsum6zvh
PubMed32744497
UniProtP62263|RS14_HUMAN Small ribosomal subunit protein uS11 (Gene Name=RPS14)

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