Structure of PDB 6xb3 Chain O

Receptor sequence
>6xb3O (length=227) Species: 46015 (Autographa californica nucleopolyhedrovirus) [Search protein sequence]
SMELYNIKYAIDPTNKIVIEQVDNVDAFVHILEPGQEVFDETLSQYHQFP
GVVSSIIFPQLVLNTIISVLSEDGSLLTLKLENTCFNFHVCNKRFVFGNL
PAAVVNNETKQKLRIGAPIFAGKKLVSVVTAFHRVGENEWLLPVTGIREA
SQLSGHMKVLNGVRVEKWRPNMSVYGTVQLPYDKIKQHALEQESCVLFYK
DSEIRITYNKGDYEIMHLRMPGPLIQP
3D structure
PDB6xb3 Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict.
ChainO
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9BG O S172 V173 Y181 K185 A188 L189 R212 R226 S173 V174 Y182 K186 A189 L190 R205 R219
BS02 9BG O H46 Q47 F48 I56 R93 I146 R147 S153 H155 H47 Q48 F49 I57 R94 I147 R148 S154 H156
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0061507 2',3'-cyclic GMP-AMP binding

View graph for
Molecular Function
External links
PDB RCSB:6xb3, PDBe:6xb3, PDBj:6xb3
PDBsum6xb3
PubMed33191912
UniProtP08358|POXIN_NPVAC Poxin (Gene Name=P26)

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