Structure of PDB 6w2t Chain O

Receptor sequence

>6w2tO (length=149) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIG
VILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKH
LERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALV

3D structure

PDB

6w2t A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate.

Chain

Resolution

3.36 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	O	G2 R3 M4 H5 G8 K9 G10 L11 S12 S14 A15 P17 R20 P47 S48 A61 R64 K70 L72 R73 K76 D87 H90 K94 V98 H101 N105 K107 D108 D110 K112 F113 R114 I116 S120 R121 R124 R127 Y128	G1 R2 M3 H4 G7 K8 G9 L10 S11 S13 A14 P16 R19 P46 S47 A60 R63 K69 L71 R72 K75 D86 H89 K93 V97 H100 N104 K106 D107 D109 K111 F112 R113 I115 S119 R120 R123 R126 Y127

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0070181	small ribosomal subunit rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6w2t, PDBe:6w2t, PDBj:6w2t
PDBsum	6w2t
PubMed	32286223
UniProt	G1SP51\|RS13_RABIT Small ribosomal subunit protein uS15 (Gene Name=RPS13)

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