Structure of PDB 6q8w Chain O

Receptor sequence
>6q8wO (length=180) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
TLKALAQSLGITLKYLFSKPVTVPYPDAPVALKPRFHGRHVLTRHPNGLE
KCIGCSLCAAACPAYAIYVEPAENDPENPVSAGERYAKVYEINMLRCIFC
GLCEEACPTGAIVLGYDFEMADYEYSDLVYGKEDMLVDVVGTKPQRREAK
RTGKPVKVGYVVPYVRPELEGFKAPTEGGK
3D structure
PDB6q8w Key role of quinone in the mechanism of respiratory complex I.
ChainO
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 O H41 C63 P64 I68 C98 I99 F100 C101 C104 H40 C62 P63 I67 C97 I98 F99 C100 C103
BS02 SF4 O C53 G55 C56 S57 L58 C59 Y91 C108 T110 I113 C52 G54 C55 S56 L57 C58 Y90 C107 T109 I112
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0005506 iron ion binding
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0050136 NADH:ubiquinone reductase (non-electrogenic) activity
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0009060 aerobic respiration
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6q8w, PDBe:6q8w, PDBj:6q8w
PDBsum6q8w
PubMed32811817
UniProtQ56224|NQO9_THET8 NADH-quinone oxidoreductase subunit 9 (Gene Name=nqo9)

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