Structure of PDB 6l4a Chain O

Receptor sequence
>6l4aO (length=97) Species: 9606 (Homo sapiens) [Search protein sequence]
HRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSA
VMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB6l4a Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
ChainO
Resolution12.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna O R40 Y41 G44 V46 R49 R63 K64 L65 R69 R83 R2 Y3 G6 V8 R11 R25 K26 L27 R31 R45
BS02 dna O H39 R40 Y41 R42 T45 R63 R72 R83 F84 Q85 R116 V117 T118 M120 H1 R2 Y3 R4 T7 R25 R34 R45 F46 Q47 R78 V79 T80 M82
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0045296 cadherin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Cellular Component
External links
PDB RCSB:6l4a, PDBe:6l4a, PDBj:6l4a
PDBsum6l4a
PubMed31711756
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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