Structure of PDB 6fml Chain O

Receptor sequence
>6fmlO (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILEL
AGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVL
LPKK
3D structure
PDB6fml Structural basis for ATP-dependent chromatin remodelling by the INO80 complex.
ChainO
Resolution4.34 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna O R29 R42 V43 G44 A45 K75 T76 R77 R14 R27 V28 G29 A30 K60 T61 R62
BS02 dna O R17 R32 R2 R17
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008150 biological_process
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6fml, PDBe:6fml, PDBj:6fml
PDBsum6fml
PubMed29643509
UniProtP0C0S8|H2A1_HUMAN Histone H2A type 1 (Gene Name=H2AC11)

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