Structure of PDB 6ci9 Chain O

Receptor sequence

>6ci9O (length=253) Species: 246196 (Mycolicibacterium smegmatis MC2 155)

MFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVAD
LSGTRGKVTAVRADVTDPEDARRTVAETVSRHGGLDIVCANAGIFPSGRL
EDLTPDDIEQVLGVNFKGTVYIVQAALQALTASGHGRVVVTSSITGPITG
YPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNIMTEGLDEMGQ
DYLDQMASAIPAGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGGQVLP
ESH

3D structure

• PDB: 6ci9 Structure and Kinetics of the S-(+)-1-Amino-2-propanol Dehydrogenase from the RMM Microcompartment of Mycobacterium smegmatis.
• Chain: O
• Resolution: 1.9 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): G18 S143 Y157
• Catalytic site (residue number reindexed from 1): G18 S143 Y157
• Enzyme Commision number: 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAP	O	G14 S16 G18 I19 R39 N40 D64 V65 N91 G93 F95 T141 S143 Y157 K161 P187 G188 N189 I190 T192 G194 L195	G14 S16 G18 I19 R39 N40 D64 V65 N91 G93 F95 T141 S143 Y157 K161 P187 G188 N189 I190 T192 G194 L195
BS02	F3V	O	F95 S143 T145 W154 Y157 G188	F95 S143 T145 W154 Y157 G188

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
• GO:0016491 oxidoreductase activity

External links

• PDB: RCSB:6ci9, PDBe:6ci9, PDBj:6ci9
• PDBsum: 6ci9
• PubMed: 29757625
• UniProt: A0QP46