Structure of PDB 6bk8 Chain O

Receptor sequence
>6bk8O (length=229) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
NIHIPRYIRNQPWYYKYLVHHRQLDIDNNSEPKIGMGIKDEFKLIFCRNC
GEAGHKEKDCMEKPRKMVLVRATDDDWDSRKDRWYGYSGKEYNELISKWE
RDKRNKIDEEIELMKLELYKDSLYRTSTRLREDKAAYLNDINSTESNYDP
KSRLYKTETLGAVDEKSKMFRRHLTGEGLKLNELNQFARSHAKEMGIRDE
IEDKEKVQHVLVANPTKYEYLKKKREQEE
3D structure
PDB6bk8 Structure of the yeast spliceosomal postcatalytic P complex.
ChainO
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 IHP O R170 K171 R80 K81
BS02 ZN O C122 C125 H130 C135 C47 C50 H55 C60
Gene Ontology
Molecular Function
GO:0000386 second spliceosomal transesterification activity
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
GO:0030628 pre-mRNA 3'-splice site binding
GO:0046872 metal ion binding
Biological Process
GO:0000350 generation of catalytic spliceosome for second transesterification step
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0071021 U2-type post-spliceosomal complex

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Cellular Component
External links
PDB RCSB:6bk8, PDBe:6bk8, PDBj:6bk8
PDBsum6bk8
PubMed29146870
UniProtQ02775|SLU7_YEAST Pre-mRNA-splicing factor SLU7 (Gene Name=SLU7)

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