Structure of PDB 5xtb Chain O

Receptor sequence
>5xtbO (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
GALFVHRDTPENNPDTPFDFTPENYKRIEAIVKNYPEGHKAAAVLPVLDL
AQRQNGWLPISAMNKVAEVLQVPPMRVYEVATFYTMYNRKPVGKYHIQVC
TTTPCMLRNSDSILEAIQKKLGIKVGETTPDKLFTLIEVECLGACVNAPM
VQINDNYYEDLTAKDIEEIIDELKAGKIPKPGPRSGRFSCEPAGGLTSLT
EPPKGPGFGVQA
3D structure
PDB5xtb Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
ChainO
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES O C135 T137 P139 C176 L177 G178 A179 C180 C100 T102 P104 C141 L142 G143 A144 C145
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:5xtb, PDBe:5xtb, PDBj:5xtb
PDBsum5xtb
PubMed28844695
UniProtP19404|NDUV2_HUMAN NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (Gene Name=NDUFV2)

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