Structure of PDB 5thp Chain O

Receptor sequence
>5thpO (length=191) Species: 9606 (Homo sapiens) [Search protein sequence]
SLIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYNNPR
VVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGR
RSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALD
TKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIF
3D structure
PDB5thp Dramatic and concerted conformational changes enable rhodocetin to block alpha 2 beta 1 integrin selectively.
ChainO
Resolution3.006 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG O S182 S184 S12 S14
External links
PDB RCSB:5thp, PDBe:5thp, PDBj:5thp
PDBsum5thp
PubMed28704364
UniProtP17301|ITA2_HUMAN Integrin alpha-2 (Gene Name=ITGA2)

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