Structure of PDB 5jut Chain O

Receptor sequence

>5jutO (length=169) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]

QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK

3D structure

PDB

5jut Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.

Chain

Resolution

4.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	O	K16 V18 N20 S22 S48 A50 R51 T56 F57 I65 A66 H68 N95 F96 S97 T99 N101 F104 G105 D107 G124 M125 D126 Y128 K142	K11 V13 N15 S17 S43 A45 R46 T51 F52 I60 A61 H63 N90 F91 S92 T94 N96 F99 G100 D102 G119 M120 D121 Y123 K137
BS02	rna	O	M9 R10 Q43 T44 V46 T70 R72 P134 R137 V138 R141 G146 T147 N150 S151 H152	M4 R5 Q38 T39 V41 T65 R67 P129 R132 V133 R136 G141 T142 N145 S146 H147

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:5jut, PDBe:5jut, PDBj:5jut
PDBsum	5jut
PubMed	27159452
UniProt	P0C0W9\|RL11A_YEAST Large ribosomal subunit protein uL5A (Gene Name=RPL11A)

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