Structure of PDB 5gm2 Chain O

Receptor sequence
>5gm2O (length=279) Species: 68180 (Streptomyces blastmyceticus) [Search protein sequence]
QVTADEVGDWYDKFGEVYHLTLGESVHCGLWFPPDAPVPQDMELVTMSSQ
AQDRYTDYLIETLDPKAGQHLLDIGCGTGRTALKAARQRGIAVTGVAVSK
EQIAAANRLAAGHGLTERLTFEVADAMRLPYEDESFDCAWAIESLCHMDR
AKALGEAWRVLKPGGDLLVLESVVTEELTEPETALFETLYAANVPPRLGE
FFDIVSGAGFHTLSLKDLSANLAMTMNVFALGVYSRRAEFTERFGAEFVD
GLLAGLGSAQETLIRKTRFFMATLRKPAV
3D structure
PDB5gm2 Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleD
ChainO
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH O G85 G87 A107 V108 Q112 D135 A136 I152 H157 M158 G75 G77 A97 V98 Q102 D125 A126 I142 H147 M148
BS02 TEX O E153 C156 H157 E181 S182 F196 Y200 L232 M236 F279 E143 C146 H147 E171 S172 F186 Y190 L222 M226 F269
BS03 SAH O Y21 V36 H37 Y11 V26 H27
BS04 TEX O Y28 L32 H37 Y18 L22 H27
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:5gm2, PDBe:5gm2, PDBj:5gm2
PDBsum5gm2
PubMed27613858
UniProtA0A077K7L1

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