Structure of PDB 5cky Chain O

Receptor sequence

>5ckyO (length=324) Species: 9606 (Homo sapiens) [Search protein sequence]

EDLLKNLLTMGVDIDMARKRQPGVFHRMITNEQDLKMFLLSKGASKEVIA
SIISRYPRAITRTPENLSKRWDLWRKIVTSDLEIVNILEASPESFFRSNN
NLNLENNIKFLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEFLQAAG
LSLGHNDPADFVRKIIFKNPFILIQSTKRVKANIEFLRSTFNLNSEELLV
LICGPGAEILDLSNDYARRSYANIKEKLFSLGCTEEEVQKFVLSYPDVIF
LAEKKFNDKIDCLMEENISISQIIENPRVLDSSISTLKSRIKELVNAGCN
LSTLNITLLSWSKKRYEAKLKKLS

3D structure

PDB

5cky Base Flipping by MTERF1 Can Accommodate Multiple Conformations and Occurs in a Stepwise Fashion.

Chain

Resolution

2.62 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	O	R92 R127 A162 S163 E165 T198 N199 R202 R350 N377 T379 K391 K394	R20 R55 A90 S91 E93 T126 N127 R130 R278 N305 T307 K319 K322
BS02	dna	O	G95 H98 R99 R130 R134 R169 S170 R202 S207 L210 S248 R251 S285 Y288 L323 A324 K327 D353 S354 S355 T358 S384 K385 R387	G23 H26 R27 R58 R62 R97 S98 R130 S135 L138 S176 R179 S213 Y216 L251 A252 K255 D281 S282 S283 T286 S312 K313 R315

Gene Ontology

	Molecular Function
GO:0003690	double-stranded DNA binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:5cky, PDBe:5cky, PDBj:5cky
PDBsum	5cky
PubMed	26523681
UniProt	Q99551\|MTEF1_HUMAN Transcription termination factor 1, mitochondrial (Gene Name=MTERF1)

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