Structure of PDB 4toe Chain O

Receptor sequence
>4toeO (length=154) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
GDKKVIQHLNKILGNELIAINQYFLHSRMWNFWGLKRLGAHEYHESIDEM
KHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKDLR
EAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYLQS
HMHE
3D structure
PDB4toe Concerted motions networking pores and distant ferroxidase centers enable bacterioferritin function and iron traffic.
ChainO
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 O E18 E51 H54 E127 E16 E49 H52 E125
BS02 FE2 O E51 E94 E127 H130 E49 E92 E125 H128
BS03 FE2 O H10 H107 H8 H105
BS04 HEM O I22 N23 F26 I49 M52 K53 I20 N21 F24 I47 M50 K51
Gene Ontology
Molecular Function
GO:0004322 ferroxidase activity
GO:0005506 iron ion binding
GO:0008199 ferric iron binding
GO:0015093 ferrous iron transmembrane transporter activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis
GO:0006880 intracellular sequestering of iron ion
GO:0034755 iron ion transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070288 ferritin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4toe, PDBe:4toe, PDBj:4toe
PDBsum4toe
PubMed25640193
UniProtQ9HY79

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