Structure of PDB 4l3c Chain O

Receptor sequence
>4l3cO (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB4l3c Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
ChainO
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide O H191 S195 E198 S251 E254 W274 E275 H191 S195 E198 S251 E254 W274 E275
BS02 peptide O Y7 E63 K66 H70 T73 H74 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 Y159 T163 W167 Y171 Y7 E63 K66 H70 T73 H74 D77 L81 Y84 R97 Y99 Y116 T143 K146 W147 Y159 T163 W167 Y171
External links
PDB RCSB:4l3c, PDBe:4l3c, PDBj:4l3c
PDBsum4l3c
PubMed24338476
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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