Structure of PDB 3tgx Chain O

Receptor sequence
>3tgxO (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]
CPDLVCYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHR
SAHNATHATYTCHMDVFHFMADDIFSVQITDQSGQYSQECGSFLLAESIK
PAPPFDVTVTFSGQYQISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAV
SPRRKLISVDSRSVSLLPLEFRKDSSYELQVRAGPMPGSSYQGTWSEWSD
PVIFQTQS
3D structure
PDB3tgx The crystal structure of the interleukin 21 receptor bound to interleukin 21 reveals that a sugar chain interacting with the WSXWS motif is an integral part of the interleukin 21 receptor.
ChainO
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN O R154 R182 W198 R154 R182 W198
BS02 MAN O T194 W195 T194 W195
Gene Ontology
Molecular Function
GO:0004896 cytokine receptor activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3tgx, PDBe:3tgx, PDBj:3tgx
PDBsum3tgx
PubMed22235133
UniProtQ9HBE5|IL21R_HUMAN Interleukin-21 receptor (Gene Name=IL21R)

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