Structure of PDB 3jsk Chain O

Receptor sequence
>3jskO (length=292) Species: 5141 (Neurospora crassa) [Search protein sequence]
GLSKPLLELMPTLGTDAFTFSPIRESTVSRAMTRRYFADLDAHAETDIVI
VGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAWLGGQLFSAMVMRK
PADVFLDEVGVPYEDEGDYVVVKHAALFTSTVLSKVLQRPNVKLFNATTV
EDLITRKHAKVRIAGVVTNWTLVSMHHDDQSAMDPNTINAPVIISTTGHD
GPFGAFSVKRLVSMKQMERLNGMRGLDMQSAEDAIVNNTREIVPGLIVGG
MELSEIDGANRMGPTFGAMALSGVKAAHEAIRVFDLRKAQND
3D structure
PDB3jsk Crystal structure of thiazole synthase Thi4 from Neurospora crassa
ChainO
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.60: cysteine-dependent adenosine diphosphate thiazole synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AHZ O V85 G86 C90 E111 A112 G118 V184 T246 T247 G248 F253 G300 M301 R311 M312 G313 M319 V51 G52 C56 E77 A78 G84 V150 T196 T197 G198 F203 G250 M251 R261 M262 G263 M269
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0008198 ferrous iron binding
GO:0016740 transferase activity
GO:0016763 pentosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000002 mitochondrial genome maintenance
GO:0009228 thiamine biosynthetic process
GO:0052837 thiazole biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3jsk, PDBe:3jsk, PDBj:3jsk
PDBsum3jsk
PubMed
UniProtQ1K6I4|THI4_NEUCR Thiamine thiazole synthase (Gene Name=NCU06110)

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