Structure of PDB 3d1n Chain O

Receptor sequence
>3d1nO (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]
NMEEIREFAKNFKIRRLSLGLTQTQVGQAMTATEGPAYSQSAISRFEKLD
ITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFT
PQAIEALNAYFEKNPLPTGQEITEMAKELNYDREVVRVWFSNRRQTLKNT
3D structure
PDB3d1n Structure of human Brn-5 transcription factor in complex with CRH gene promoter.
ChainO
Resolution2.51 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna O R158 T164 Q165 Q182 S183 S186 K190 R235 K236 R238 T239 N284 R16 T22 Q23 Q40 S41 S44 K48 R93 K94 R96 T97 N142
BS02 dna O S181 S183 R235 R238 Q287 S39 S41 R93 R96 Q145
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3d1n, PDBe:3d1n, PDBj:3d1n
PDBsum3d1n
PubMed19450691
UniProtQ14863|PO6F1_HUMAN POU domain, class 6, transcription factor 1 (Gene Name=POU6F1)

[Back to BioLiP]