Structure of PDB 2x4y Chain O

Receptor sequence
>2x4yO (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
DSPLDALDLVWAKCRGYPSYPALIIDPKMPREGMFHHGVPIPVPPLEVLK
LGEQMTQEAREHLYLVLFFDNKRTWQWLPRTKLVPLGVNQDLDKEKMLEG
RKSNIRKSVQIAYHRALQHRSKV
3D structure
PDB2x4y Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
ChainO
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide O R1094 Y1096 Y1099 R1110 E1111 G1112 F1114 P1119 P1121 L1130 F1147 K1151 R1152 T1153 W1154 R15 Y17 Y20 R31 E32 G33 F35 P40 P42 L51 F68 K72 R73 T74 W75
External links
PDB RCSB:2x4y, PDBe:2x4y, PDBj:2x4y
PDBsum2x4y
PubMed20400950
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

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